Agilent e-Seminar: A Metallomics Approach for Analysis of Biological and Environmental Compounds via ICP-MS
May 17, 2006
Presenter: Professor Joe Caruso, University of Cincinnati
Recent advances in ICP-MS instrumentation have produced lower detection
limits, greater spectral resolution, and markedly enhanced capabilities
to probe elements that were impossible a decade ago. As reliable and
robust high resolution and collision/reaction cell ICP-MS instruments
have emerged, the power of ICP-MS has been enhanced for numerous
metals/metalloids and important non-metals. Se and P are the elemental
targets for this e-seminar.
Selenium
is a fascinating element exhibiting toxicant, cancer chemopreventive
and Hg antagonist properties depending on its concentration, chemical
form and the genetic disposition of the plant or organism.
This talk
will discuss these developments, illustrations of these three aspects
of Se utilizing multiple chromatographic methods interfaced to
different mass spectrometries to speciate from small Se to large Se
molecules. P is an important element and with the Agilent 7500ce
system, it may be detected at its natural m/z of 31.
The
discussion will focus on the application of chromatography ICP-MS
techniques important phosphorus containing small molecules such as fire
retardants and chemical warfare agent hydrolyzates.