Welcome to the July issue of EVISA's Speciation Newsletter !

Speciation analysis is often performed by using the ICP-MS as detection system. The reason is very simple: ICP-MS allows for the determination of nearly all elements, can even be used to determine isotopes and is very sensitive.

However, since the ICP is destroying all molecular information, ICP-MS can be used for speciation analysis only by adding a separation method. Liquid chromatography is the most often used technique, offering a wide range of separation modes (ion exchange, reversed phase, size-exclusion, affinity, hydrophobic interaction, etc.) and can be easily interfaced to the ICP.

The challenges come up when looking at the details. The eluent flow rate has to be adapted at the sample uptake rate of the nebulizer system or the nebulizer system has to be chosen for accepting the eluent flow rate.

The mobile phase has to be selected in a way that can be tolerated by the ICP. It should not contain too much salts that would contaminate the interface. The amount of organic solvents should not surpass the maximum plasma solvent load tolerance and oxygen has to be added to the plasma gas in order to avoid carbon build-up on the sampler cone. Gradient elution will most often lead to changing plasma conditions hindering component independent calibration.

Researchers from the University of Graz tried to circumvent such problems when using RP-HPLC as the separation mode. They propose to use 1,2-Hexanediol as eluent for RP-HPLC coupled to ICP-MS. This eluent avoids the necessity to operate the ICP-MS in the organic mode improving the detection power of the hyphenated system (see the news below).

Another problem might occur, when very different concentrations of species have to be determined in a single run. While the ICP-MS has a very wide linear working range of approaching 8-10 orders of magnitude, such concentration differences cannot be accepted within a single chromatographic run because of memory effects within the sample introduction system. This is the problem that Chinese researchers were facing when trying to analyse platinum-chloride complexes as impurities in platinum-based drugs that should not surpass 0.1 %. The researchers achieved the goal by using an on-line switching technology meant to bypass the Pt-drug elution peak to waste instead of feeding it to the ICP-MS (see the news below).  

During the last two months, some conferences took place with participants meeting in person. While everybody is looking for meeting colleagues, such meetings are unfortunately not without risks since the number of infections is still very high in many countries. We have heard that some participants came back from such meetings being infected. Take care !
EVISA is keeping you updated with what is going on in speciation analysis. In this section you will find news about the most current research results, about trends, legal issues and information from manufacturers in the field of speciation analysis.

With all the links to further information and publications the News archive is a valuable collection of "hot topics" in speciation analysis. We continuously update even former news with new links and information so that all news are actual all the time.

Ultra-sensitive speciation analysis of inorganic platinum-chloride complexes in platinum-based drugs by HPLC-ICP-MS
Chinese researchers have developed a method for the determination of platinum chloride complexes as impurities of platinum-based drugs.

1,2-Hexanediol as eluent for HPLC Enables Coupling with ICPMS under Standard Conditions
Researchers from the University of Graz propose to use 1,2-Hexanediol as eluent for RP-HPLC coupled to ICP-MS. This eluent avoids the necessity to operate the ICP-MS in the organic mode improving the detection power of the hyphenated system.

With a list of about 50 current entries EVISA is informing you about interesting events and keeps you updated with their deadlines. By consulting our list of deadlines you won't miss the opportunity for early registration at reduced fee or the chance to submit your contribution in time.
 more infos...

ICASS 2022: 64th International Conference on Analytical Sciences and Spectroscopy
Date:     August 8,2022 - August 10,2022
Location:     Kingston, Ontario K7M 9E3, Canada
July 2,2022    Submission of abstracts for late poster presentations
July 3,2022    Regular registration
July 14,2022    Hotel reservation (discounted group rate)

ICP-MS User Meeting 2022
Date:     September 5,2022 - September 8,2022
Location:     Montanuniversität Leoben,
June 30,2022   Hotel room reservation within conference contingent
July 31,2022    Registration

ISC2022: 33rd International Symposium on Chromatography
Date:     September 18,2022 - September 22,2022
Location:     Budapest Congress Center, Budapest, Hungary
June 30,2022    Early registration at reduced fee

Terrae Rarae 2022
Date:     September 27,2022 - September 29,2022
Location:     Leipzig
June 30,2022    Submission of abstracts
June 30,2022    Registration

SciX 2022
Date:     October 2,2022 - October 7,2022
Location:     Northern Kentucky Convention Center, Greater Cincinnati, Northern Kentucky,
August 1,2022    Submission of abstracts for poster presentation

Airmon 2022: 10th International Symposium on modern principles of air monitoring and biomonitoring.
Date:     November 7,2022 - November 10,2022
Location:     Bristol, United Kingdom
July 22,2022    Early registration at reduced fee

Please do not hesitate to inform us in case that your conference related to speciation analysis is missing in our Agenda.

ISM 2022: 8th International Symposium on Metallomics
Location: Kanazawa Chamber of Commerce and Industry, Kanazawa, Japan
Date: 11.07.2022 - 14.07.2022

EWLA 2022: European Workshop on Laser Ablation
Location: Bern, Switzerland
Date: 12.07.2022 - 15.07.2022

EUROBIC 2022 – 16th European Biological Inorganic Chemistry Conference
Location: Grenoble, France
Date: 17.07.2022 - 21.07.2022

EuroBIC-16: 16th European Biological Inorganic Chemistry Conference
Location: Grenoble, France
Date: 17.07.2022 - 21.07.2022

Virtual: 15th International Conference on Mercury as a Global Pollutant
Location: Virtual
Date: 24.07.2022 - 29.07.2022

NEMC 2022: National Environmental Monitoring Conference
Location: Hyatt Regency in Crystal City, Virginia
Date: 01.08.2022 - 05.08.2022


EVISA provides information about open positions for Ph.D. students, PostDocs and permanent staff in the field of speciation. Looking to fill a vacancy or needing a new career challenge? Either way this service is FREE. Many laboratories and research facilities (from Greenland to Crete) have already found their highly educated stuff through this service by EVISA. If you would like to post an open position here, please contact us at info@speciation.net !


Europe: Mercury Biogeochemistry
The EU H2020 programme is financing a Marie-Curie training network on 'mercury biogeochemistry' over the next four years (2020-2023). A total of 15 PhD positions are open throughout Europe on a variety of topics, some including ICPMS or mass spectrometry.




LGC, Teddington, UK: Senior Researcher Bio-clinical Speciation Analysis
UK National Measurement Laboratory (NML) is looking for a Senior Researcher. The job holder will supervise and deliver project work in the area of bio-clinical speciation analysis, initially focusing on the development of methodology for the accurate quantification and identification of key biomarkers of metal metabolism/disorders (e.g. metalloproteins) for disease diagnostics and therapy, down to the single cell level.


EVISA's directory of scientist is a versatile tool to facilitate contact with scientists in the field of speciation and related sciences. The directory is fully searchable for names, addresses, research topics etc.  You should bookmark this directory as an always up-to-date address book. (In order to hinder SPAM robots for collecting the E-mail accounts, we hide them in a special format).

More than 290 active scientists in the field of speciation analysis already joined the directory. Join this great directory that is extensively linked to all type of other information on this site, such as homepages, conferences and literature.

If your entry is still missing in this directory, please contact us at info@speciation.net.



EVISA provides an easy access to external information. Our database contains more than 2800 links to relevant information from numerous top scientific resources spread over the whole Web. The database is searchable both via full-text and categories such as elements, type of species and type of information. We are permanently updating our links section.

If your web site is missing here, please e-mail your link information to info@speciation.net.


This issue of evisa's Speciation Newsletter has been sent to you by EVISA, because you have registered for this service. If you would like to modify your user account, please log-in on EVISA's web portal at http://www.speciation.net with your username and password and edit your user account.

Please feel free to pass this Speciation Newsletter to others who may benefit from EVISA. If you have any contributions or suggestions, please send these to editors@speciation.net.

This is a post-only e-mail.  Please do not reply to this message.  For all inquiries, problems or suggestions regarding this service, please visit http://www.speciation.net or contact info@speciation.net

Copyright 2022 EVISA 
All rights reserved.  Any unauthorized use, reproduction, or transfer of this message or its contents, in any medium, is strictly prohibited.  No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior written permission of EVISA.

No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. The Newsletter represents only the opinion of the authors and does not necessarily reflect the opinion of the European Community. The European Community is not responsible for any use that might be made of the information provided.