tandem mass spectrometry

Tandem Mass Spectrometry, usually referred to as MS/MS, involves the use of 2 or more mass analyzers. It is often used to analyze individual components in a mixture. This technique adds specificity to a given analysis. 
The basic idea of MS/MS is a selection of a m/z of a given ion formed in the ion source, and subject this ion to fragmentation, usually by collision with inert gas (eg. Argon). The product ions are then detected. This is a powerful way of confirming the identity of certain compounds and determining the structure of unknown species. So MS/MS is a process that involves 3 steps: ionization-mass selection-mass analysis.

MS/MS could be performed on instruments such as triple quadrupole (QQQ), ion trap, time of flight, fourier transform, etc... The triple quadrupole is the most frequently used mass spectrometer for MS/MS, perhaps because of the cost and ease of use among other factors.




The term "tandem mass spectrometry" was found in the following pages:

Instrument database: Bruker Daltonics - maXis Ultra High ResolutionTOF
Journals database: Mass Spectrometry Letters
Instrument database: Bruker Daltonics - ultraflex II & ultraflex II TOF/TOF
Instrument database: Bruker Daltonics - maXis 4G - UHR-TOF
Quantification of polybrominated diphenyl ethers by means of GC-ICP-MS | EVISA's News
Triple Quad ICP-MS: Pushing the limits for quantitation of phosphorus and sulfur | EVISA's News
ESI-MS: The tool for the identification of chemical species | EVISA's News
Link database: NEMI: Method Number: 557: Haloacetic Acids, Bromate, and Dalapon in Drinking Water by IC-ESI-MS/MS
EU seeking to restrict chemicals in tattoo inks over cancer fears | EVISA's News
Tools for elemental speciation analysis
Determination of Glyphosate in Rice with HPLC-ICP-MS/MS | EVISA's News
Determination of methylmercury complexes with low molecular mass thiols | EVISA's News
Instrument database: Bruker Daltonics - autoflex II & autoflex II TOF/TOF
Tools for elemental speciation
Speciation of Germanium in Environmental Water Reference Materials by Hydride Generation and Cryotrapping in Combination with ICP-MS/MS | EVISA's News
Researchers found new sulfur-containing metabolites in the urine of rats exposed to arsenite | EVISA's News
Instrument database: Bruker Daltonics - maXis HD™ - UHR-TOF Mass Spectrometer
Directory of scientists: José Luis Gómez Ariza
On-column internal standardisation as an alternative calibration strategy for speciation analysis | EVISA's News