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Instrument Database:
Beckman Coulter Inc. - CESI 8000 High Performance Separation-ESI Module
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| Year of introduction |
2011 |
| Status |
available |
| Company |
Beckman Coulter Inc.
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| Categories |
Separation: Electrophoresis, Capillary
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The CESI 8000 was developed in collaboration with mass spectrometry researchers covering a number of applications. They sought to expand their range of detection and increase sensitivity. In order to achieve this goal, a low flow pre-MS separation technology was integrated with a novel ESI coupling technology. The CESI 8000 is based on a new front-end separation-and ionization technology called CESI, which fully integrates the high efficiency and ultra-low flow characteristics of capillary electrophoresis (CE) with electrospray ionization (ESI) in a single dynamic process within the same device. Reduction of flow with ESI into the low nanoflow region serves to significantly improve ionization efficiency as well as reduce ion suppression of co-migrating analytes. With CESI we are able to generate stable and robust electrospray with bulk flows of electrolyte at or below 10 nl/min, that when combined with the orthogonal selectivity provided by CE allows for increased coverage and sensitivity.
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| Specifications |
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| Width: | 25 in (63.5 cm) | | Height: | 29.2 in (74.2 cm) | | Height with Door Open: | 38.8 in (98.6 cm) | | Depth: | 28.4 in (72.1 cm) | | Weight: | 188 lbs (85.3 kg) includes photodiode array detection | | Electrical Requirements: | Voltage 100 - 240 V 50/60 Hz | | Buffer Tray: | 2 x 36 2 mL vials, 4 x 25 mL trays | | Current Range: | 3 to 300 μA programmable at 0.1 μA Increments | | Pressure Range: | -5 to +100 psi | | Sample Tray: | 2 x 96-well plates, 2 x 48 2 mL vials, 2 x 48 0.5 mL vials, 2 x 48 PCR vials | | Voltage Range: | 1 - 30 kV (1 - 10 kV for injections), Programmable in 0.1 kV increments, Reversible voltage programmed through user interface. |
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