Instrument Database:
Bruker Biospin - AVANCE™ II
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Status |
available |
Company |
Bruker Biospin
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Categories |
Spectrometer ( Molec. ): NMR |
The fundamentally superior precision and stability of fully digital signal generation and processing was introduced and established by the precedent-setting series of AVANCE™ NMR spectrometers. With its digital advantage, the Bruker AVANCE™ series set revolutionary standards for performance, long-term reliability and ease-of-use, whether for routine applications or the most demanding research.
The next-generation Avance II NMR spectrometer series features a second-generation digital receiver technology (2G-DR™), a new milestone in NMR detection fidelity. The 2G-DR provides significant benefits for the most demanding NMR applications, e.g., materials science, polymer analysis, trace analysis, LC-NMR, MR imaging and structural biology, particularly for measurements with Bruker BioSpin\'s ultrasensitive CryoProbes™. The new 2G-DR technology represents a further dramatic improvement with: More than a four-fold increase in digital resolution and unsurpassed dynamic range.
- Higher digitization rates and an order of magnitude increase in the over-sampling rate.
- More than an order of magnitude increase in the maximum bandwidth with digital filtering.
- An order of magnitude increase in the maximum bandwidth for digital quadrature detection (DQD).
- A single receiver for even the most demanding liquids, solids and imaging applications.
Thus, the Avance II offers significant performance benefits:
- Enhanced digital filtering for applications requiring very large spectral widths (13C or 19F NMR, paramagnetic proteins, liquid crystals, solids NMR, ultra-fast MR imaging).
- More efficient detection of weak signals in the presence of very strong signals and improved utilization of the extreme sensitivity provided by our CryoProbe technology.
- Unsurpassed suppression of intermodulation distortion and flat baselines for high-dynamic-range samples, even with many intense signals.
- Enhanced DQD capabilities with artifact reduction for larger spectral widths.
The Avance II is the logical continuation of the major technological improvements introduced with the Avance series over the past decade, and it is the dream machine for solids NMR. The digital receiver benefits that have been generally available for liquids NMR, can now be enjoyed by the solids NMR community. Key Features:
- AQS/2 Channel Concept
- Digital Lock
- Power Amplifiers
- Solids
- Software
- Modular Concept
- Digital Signal Routing
- Gradient Spectroscopy
- Magnets
- Workstations
- Oversampling & Digital Filtering
- 2G-DR Digital Receiver Technology
- Preamplifiers
- Gradient Amplifiers
- Variable Temperature Unit
Flexibility for all Applications
A full range of NMR capabilities is available for the AVANCE II , including Micro-Imaging, CPMAS, MQ-MAS, wide-line NMR of solids and CRAMPS. A variety of options for gradient-assisted spectroscopy (GRASP) are also available, utilizing one or three field gradients. Systems may be equipped with a sample changer for completely automated analysis of up to 120 liquid samples or 30 CPMAS solid samples.
The fantastic performance of the AVANCE II in high resolution (HR) and particularly in Solids Spectroscopy has been obtained through the continual development of RF and digital technologies. This also allowed for surperior compactness of the Acquisition System (AQS) module, which houses the complete acquisition electronics, from frequency generation to receiver and digitization.
Through its advanced modular design the AVANCE II can be optimally configured for any modern application: from classical analytical work to the most demanding structural proteomics; from high-throughput screening to high-power solids NMR to microimaging. The AVANCE II can be delivered in a variety of configurations, ranging from a minimum-footprint microbay system (for applications utilizing one, two, or three frequency channels) up to a three cabinet instrument fully equipped for high power solids NMR with four or more channels.
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