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Instrument Database:
Teledyne CETAC Technologies - CEI-100 Capillary Electrophoresis Interface for ICP-MS
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| Year of introduction |
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| Status |
available |
| Company |
Teledyne CETAC Technologies
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| Categories |
Hyphenated Techniques: CE-ICP-MS
Separation: Electrophoresis, Capillary
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CETAC Technologies in collaboration with Dr. Andreas Prange and Dr. Dirk Schaumloffel from the GKSS Research Center (Germany) has developed a simple, efficient and robust Capillary Electrophoresis (CE) interface for ICP-MS. The CEI-100 interface maintains the high resolving power of CE while utilizing the high sensitivity and multi-element capability of ICP-MS. Through the calculation of optimal fluid mechanical flow properties, the CEI-100 provides the following benefits:- Stable, high resolution
electrophoretic separation - Independent optimization of
electrophoretic and nebulizer flows - Low dead volume to preserve
the high resolution of CE - Minimal dilution (make-up liquid flow
rate of <10 µl/min) - Extremely low sample consumption
(<1 µl/min) - Elimination of detrimental secondary
laminar flows within the CE capillary
CEI-100 components include a specialized low-flow microconcentric nebulizer, spray chamber, connecting cross-piece fitting, and mounting stand. The mounting stand includes positions to hold buffer and rinse solutions. A number of application areas for the CEI-100 are listed below. A list of references is available. Applications- Metals in complex biomolecular systems
- Gold-Drug metabolic pathways
- Platinum-Protein interaction in chemotherapeutic research
- Metallothioneine studies (e.g. in context with Alzheimer\'s disease)
- Toxicological studies
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