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Instrument Database:
Shimadzu Europe - Nexera UC Preparative SFC system
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| Year of introduction |
2019 |
| Status |
available |
| Company |
Shimadzu Europe
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| Categories |
Chromatography: SFC
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The Nexera UC Prep is a new preparative supercritical fluid chromatography system that offers both the high basic performance developed for the previous Nexera UC model and original state-of-the-art preparative SFC technologies.
The system has been awarded a Pittcon 2019 Gold Excellence Award, recognizing ingenuity and innovation. Shimadzu’s Semi-Prep SFC is the fruit of a collaborative effort by pharma and private industry, serving as the model for future product design with impact. The company has worked closely together with the Enabling Technologies Consortium (ETC). This group of pharmaceutical and biotechnology companies has allied to speed up the process of creating technologies necessary for their projects. They work with third parties to discuss ideas, share information and collaborate on the development of new enabling technologies. Unparalleled performance, unparalleled flexibility Nexera UC Prep resolves a number of issues in preparative tasks, reducing labor and improving efficiency while fitting into pre-existing workflows. It provides flexible system configurations in a compact design, requiring low installation space and enabling maximum use of lab resources. The Nexera UC Prep is part of Shimadzu’s Nexera UC platform, which accommodates a wide variety of analyses and purifications. A Nexera UC Prep system can be configured according to user specifications for optimum performance of the desired purification function, including chiral or achiral purifications, single injections, stacked injections and fraction collections from several microliters to liters. This complete SFC solution reduces the need for costly and hazardous solvents used in normal phase prep LC, while shortening purification run time and dry down time. Innovative technologies include a flexible format, combination injector/fraction collector, and CO2 pump with integrated chiller requiring less lab space, thereby enabling benchtop use. The novel and patented “LotusStream” gas-liquid separator technology ensures higher recovery and lower carryover than earlier prep SFC systems. Its elegant design reduces the total size of the recovery system and allows for easy rinsing compared to earlier cyclone-style or centrifugal type gas-liquid separating systems. The newly developed, easy-to-use “Prep Solution” software streamlines operations. It simplifies configuration of parameter settings and greatly increases efficiency of the preparative workflow.
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