Journal of Chromatography B

The Journal of Chromatography B addresses advancements in and applications of analytical methodologies related to drugs, other biologically active compounds, metabolites, biomarkers as well as to bio-polymers such as proteins, peptides, nucleic acids, glycans. The areas considered include:

• clinical analysis, therapeutic drug monitoring, pharmaceutical analysis, toxicological analysis, bio-environmental analysis and novel approaches to sample preparation in analysis of biological matrices.
• the qualitative and quantitative analysis of biopolymers including proteins, peptides and their post-translational modifications as well as nucleic acids and glycans.
•  the screening and profiling of body fluids, tissues, biological matrices and system related to monitoring the level of active substances, including metabolites, biomarkers and toxicants.
• the comparative analysis of biological systems using proteomics, genomics, metabonomics and other "omics" including novel ways of data handling and interpretation.
• preparative aspects related to separation and isolation of bioactive compounds including biopolymers.

Analytical techniques covered include the various facets of chromatography, electrophoresis and related methods, including mass spectrometry and affinity-based methodologies.