metallodrugs

Term used to define a pharmaceutical, having a activity center containing a metal. Platinum (cisplatin, carboplatin) and gold (Auranofin) compounds are well-known in cancer therapy whereas some other gold compounds (aurithiomalate, aurothioglucose) are important antiarthritic drugs. A wide range of Tc compounds (e.g. Tc-labelled antibodies, Tc-mercaptoacetyl glycine complex) are used for diagnostic imaging of renal, cardiac and cerebral functions and of various forms of cancer. Gadolinium (III) polyaminopolycarboxylic crown complexes are widely used as contrast agents in magnetic resonance imaging.



The term "metallodrugs" was found in the following pages:

Global policy on the use of mercury as a preservative in vaccine called discriminatory | EVISA's News
Directory of scientists: María Montes-Bayón
New Studies Question Safety of MRI Contrast Agents | EVISA's News
Chemical Speciation Modeling | EVISA's News
Research fields related to elemental speciation
Incorporation of rare earth elements in the shell of freshwater mussels as an indicator for their bioavailability from polluted river water | EVISA's News
Chemical speciation analysis for the life sciences | EVISA's News
Gadolinium found in the brain of a patient two years after having received a Gd-based contrast agent for medical imaging | EVISA's News
Link database: NL: Groningen Research Institute of Pharmacy (GRIP)
Interaction of gadolinium-based contrast agents with humic substances | EVISA's News
New Strategy for Speciation Analysis of Gadolinium retained in Bone after Application of MR Contrast Agents | EVISA's News
Identification and quantification of potential metabolites of Gd-based contrast agents | EVISA's News
Liquid-liquid extraction in speciation analysis | EVISA's News
Themed Issue "Metallomics 2011" now available | EVISA's News
The retention of gadolinium in the human body following the use of gadolinium-based MRI contrast agents: a call to action for analytical chemists | EVISA's News
Special issue on "Advances in speciation techniques and methodology" available | EVISA's News
Journals database: Metallomics
Books and Special Issues on Elemental Speciation (published since 2006) | EVISA's News
Efficiency of some papillomavirus vaccines is reduced in the presence of thimerosal | EVISA's News
Speciation analysis of Gadolinium-based contrast agents using hydrophilic interaction liquid chromatography hyphenated with inductively coupled plasma-mass spectrometry by avoiding organic solvents | EVISA's News