metallodrugs

Term used to define a pharmaceutical, having a activity center containing a metal. Platinum (cisplatin, carboplatin) and gold (Auranofin) compounds are well-known in cancer therapy whereas some other gold compounds (aurithiomalate, aurothioglucose) are important antiarthritic drugs. A wide range of Tc compounds (e.g. Tc-labelled antibodies, Tc-mercaptoacetyl glycine complex) are used for diagnostic imaging of renal, cardiac and cerebral functions and of various forms of cancer. Gadolinium (III) polyaminopolycarboxylic crown complexes are widely used as contrast agents in magnetic resonance imaging.



The term "metallodrugs" was found in the following pages:

Impressions from the 6th Metallomics Symposium | EVISA's News
The retention of gadolinium in the human body following the use of gadolinium-based MRI contrast agents: a call to action for analytical chemists | EVISA's News
Link database: Hong Kong: Open Laboratory of Chemical Biology: C.-M. Che (HKU)
Directory of scientists: Chethaka Kahakachchi
Combined speciation analysis and elemental bioimaging provides new information about the retention of gadolinium in kidney following the application of some MRI contrast agents | EVISA's News
Speciation analysis for cancer diagnosis | EVISA's News
EMA Issues Final Opinion Limiting Gadolinium Contrast Agents in Body Scans | EVISA's News
New Strategy for Speciation Analysis of Gadolinium retained in Bone after Application of MR Contrast Agents | EVISA's News
Directory of scientists: Katarzyna Pawlak
Speciation analysis of Gadolinium-based contrast agents using hydrophilic interaction liquid chromatography hyphenated with inductively coupled plasma-mass spectrometry by avoiding organic solvents | EVISA's News
Link database: Australia: University of Sydney: Group of Peter A. Lay
Identification and quantification of potential metabolites of Gd-based contrast agents | EVISA's News
Chemical speciation as a discipline in Analytical Chemistry Definitions
Liquid-liquid extraction in speciation analysis | EVISA's News
Global policy on the use of mercury as a preservative in vaccine called discriminatory | EVISA's News
Themed Issue "Metallomics 2011" now available | EVISA's News
Detection of Gd-based contrast agent in the skin of a patient eight years after administration | EVISA's News
European Medicines Agency recommends to pull linear Gadolinium-based MRI contrast agents from market | EVISA's News
Copper molecule shows promise in fighting against cancer | EVISA's News
FDA investigating risk of gadolinium contrast agent brain deposits | EVISA's News