MALDI

Matrix assisted laser desorption ionization mass spectrometry (MALDI) is a mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.



The term "MALDI" was found in the following pages:

Instrument database: Shimadzu Europe - AXIMA Resonance - MALDI-TOF Mass Spectrometer
Instrument database: Waters Corporation - MALDI micro MX
Instrument database: Agilent Technologies Inc. - 1260 Infinity Micro-scale Purification/Spotting System
Instrument database: Applied Biosystems - 4800 Plus MALDI TOF/TOF™ Analyzer
Instrument database: Applied Biosystems - BIOiTRAQ™ TT System
CSI 2015: Colloquium Spectroscopicum Internationale | EVISA's Agenda of Events
Instrument database: Bruker Daltonics - esquire4000
ISTERH 2015: Recent Advances in Trace Element Research in Health and Disease | EVISA's Agenda of Events
Brief summary: Speciation analysis for the study of metallodrugs and their biomolecular interactions | EVISA's News
Directory of scientists: H. M. "Skip" Kingston
Colloquium Spectroscopicum Internationale (CSI XXXVI) | EVISA's Agenda of Events
Instrument database: Bruker Daltonics - autoflex II & autoflex II TOF/TOF
Company database: LTB Lasertechnik in Berlin GmbH
Directory of scientists: H. M. "Skip" Kingston
ESAS 2014: European Symposium on Atomic Spectrometry / 15th Czech -Slovak Spectroscopic Conference | EVISA's Agenda of Events
Instrument database: Waters Corporation - MALDI Q-Tof Premier
Instrument database: Agilent Technologies Inc. - 1260 Infinity Nanoflow LC System for MS
Company database: Waters Corporation
Instrument database: Bruker Daltonics - autoflex™ speed MALDI-TOF(/TOF)
Instrument database: Applied Biosystems - 4700 Proteomics Analyzer