Trace element determination for diagnosis and therapy control.
Method developments, especially hyphenated techniques for speciation projects (also from the general analytical services).
Trace element speciation in the frame of neurodegeneration research, specifically Manganese- Iron and Selenium speciation in the frame of environmental medicine and neurotoxicology.
Within this field our newly developed CE-ICP-MS method is employed for Iron Redox Speciation of Ferritin, Fe2+ and Fe3+, paralleled by GSH/GSSG differentiation, both helping to characterize oxidative stress and helping to explain steps of ferroptosis mechanism.