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Development of advanced analytical chemistry techniques
for determining metal species, including metal containing nanoparticles, in
environmental and biological matrices, and for investigating their interaction
with biomolecules. In order to achieve this, a wide range of separation
techniques (HPLC, nanoHPLC, ion mobility spectrometry, affinity chromatography)
coupled on-line with mass spectrometry (electrospray, sonic-spray ionization,
nanoelectrospray, atmospheric pressure chemical ionization, inductively coupled
plasma mass spectrometry ICP-MS) are being developed and used. Single particle
ICP-MS is also being developed for nanoparticle counting and characterization.
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