Biopharmaceutics and Drug Disposition

Biopharmaceutics & Drug Disposition publishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs. These include:

• animal and human pharmacological studies that focus on therapeutic response. pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites,
• in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in man
• studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition,
• simulation and modeling in drug discovery and development
• theoretical treatises
• includes themed issues and reviews

• bioavailability studies reporting only on simple PK parameters such as Cmax, tmax and t1/2 without mechanistic interpretation
• analytical methods

Reports must contain current citation of the literature and convey new information.