In 1988, a group of scientists at Eka Chemicals in Sweden introduced a silica-based packing material that greatly improved the effectiveness of liquid chromatography! What made the new packing material so unique was the combination of high pore volume and surface area, together with a very high mechanical stability. Even today this combination of properties is unmatched by other chromatography packings on the market.
It means you can load more sample onto the column, while withstanding the high mechanical pressure of a dynamic axial compression column. High production rates are achieved by using small, efficient particles packed in short column beds, and by applying short cycle times. The R&D team called this: "The Kromasil High Performance Concept."
While Kromasil typically represents less than 10 percent of your total separation costs, it can have a significant impact on your total costs. Solvent consumption can be reduced, in some cases up to 90 percent compared with other packings — a substantial saving when you consider that solvent costs are typically 50 to 80 percent of total separation cost.
