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Instrument Database:
Varian Inc. (Part A) - ProStar 430 AutoSampler
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| Year of introduction |
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| Status |
historical ( out of sale ) |
| Company |
Varian Inc. (Part A)
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| Categories |
Automation: Autosampler (LC)
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The 430 AutoSampler is Varian's most versatile HPLC injection system. Compatible with all types of 96- or 384-well plate formats as well as standard HPLC vials, the 430 is ideal for any of today’s demanding HPLC applications. Performance- Accommodates variable well plate sample trays -- While the 430 handles a wide variety of well plates, it also holds conventional 2-ml HPLC vials. With a touch of a button, quickly select from 96-deep-well plates, standard 96-well plates, 384-well plates, PCR tubes, or 48 standard vials.
- Ideal for high throughput LC and LC-MS -- fast cycle times allow analysis of more than 1,500 samples a day.
- Metal-free sample path for sensitive samples -- A completely biocompatible PEEK injection valve and sample needle are available.
- For precise sampling, the vial is slightly pressurized by an internal compressor while the syringe drive mechanism accurately draws the desired volume into the valve's loop. Without sample loss, the microliter pick-up technique positions the sample plug into the center of the loop.
- Precise, reliable injections -- The 430 AutoSampler’s breakthrough loop injection technique with Pressure Assisted Sampling (PAS) combines precision with simplicity in a highly reliable design. PAS eliminates air bubble problems and sample contamination because it doesn’t use a needle port that can easily wear out. The 430 AutoSampler’s high-resolution syringe drive partitions syringe movement into 0.004-µl steps and achieves incredible injection precision at 1 µl or less.
- Choose from three injection modes -- 1. Full loop injection mode: when there is excess sample, the 430 overfills the installed injection loop for the best reproducibility (RSD < 0.3%). 2. Partial loop-fill injection mode: programmable injections from 1 µ l to 60% of loop volume offer precision (RSD < 0.5%) and minimize sample loss. 3. Microliter pickup injection mode: the exact injection volume is sampled. Then, a wash solvent positions the sample into the loop. There is no sample loss and reproducibility is better than 1.0% RSD.
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