SRM 1950 - Metabolites in Human Plasma

This Standard Reference Material (SRM) is intended primarily for validation of methods for determining metabolites such as fatty acids, electrolytes, vitamins, hormones, and amino acids in human plasma and similar materials. This SRM can also be used for comparison of measurement technologies used in metabolomic studies and for quality assurance when assigning values to in-house reference materials. The SRM is intended to represent “normal” human plasma. A unit of SRM 1950 consists of five vials, each containing approximately 1.0 mL of plasma. The development of SRM 1950 was a collaboration between the National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).  Analyses   for value assignment were performed by NIST and the Centers for Disease Control and Prevention (CDC), Atlanta, GA. All certified and reference valu  es are based on the agreement between the results from NIST methods and from the CDC, where available. The associated uncertainties are expressed at the 95 % level of confidence.  Values are reported in mass   fraction, mass concentration, and amount-of-substance (molar) concentration units as appropriate.  

Keywords: Biological material, Body fluid, Blood, Trace elements, Heavy metals,  Speciation analysis, Selenium speciation