Applied Biosystems - 4700 Proteomics Discovery System

The 4700 Proteomics Discovery System is the world's first MALDI tandem time-of-flight mass spectrometer with TOF/TOF™ optics. This comprehensive system includes sophisticated bioinformatics and enabling chemistries.

• Fast mass analysis enables flexible experimental design to maximize laboratory productivity.
• Innovative results dependent analysis using RDA™ Software for automated, confident protein identification.
• ICAT® reagents enable targeted expression-dependant analysis.
• Exclusive de novo sequencing and proprietary Pro BLAST Search Engine enables you to link de novo results to homologous proteins from sequence databases.
• Direct link to the Applied Biosystems PANTHER™ Protein Classification System adds biological context and molecular-function information to your identified proteins.

A More Direct Route to the Biology
The 4700 Proteomics Discovery System takes you past the data to the understanding of biology with exceptional mass spectral data, reproducible protein identification, and in-depth, biologically relevant information from the PANTHER™ Protein Classification System. Sensitivity, accurate mass, wide dynamic range, and comprehensive protein analysis software enable quick and reliable protein identification. Complete automation of the analysis process allows you to enhance productivity and solve complex biological problems.

Experimental Freedom
The speed, flexibility, and ease-of-use of this system accommodate a wide variety of protein- and peptide-based workflows, enabling you to expand the depth of analysis of gel-based or multidimensional liquid chromatography (MDLC) experiments. Innovative RDA™ Software automates and optimizes instrument performance for acquisition and analysis, providing answers to your biological questions—faster.

Confident Protein Identification with Biologically Relevant Information
As a proteomics researcher, your ability to confidently identify proteins with biologically relevant information is critical. Using the 4700 Proteomics Discovery System's RDA™ Software, you can automate the selection of MS/MS data based on your PMF protein identifications and review extensive biological information from the PANTHER™ Protein Classification System at the click of a button.

Expression Dependent Analysis for Biomarker Discovery
When you combine the 4700 Proteomics Discovery System with cleavable ICAT® Reagents, true differential-expression biomarker discovery becomes a reality. Finally, you can target only the most highly expressed proteins to focus on the biological transformations that cause disease. And using the PANTHER™ Protein Classification System, key information on protein molecular functions, biological processes, and regulatory pathways is at your fingertips.