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Instrument Database:
Foss A/S - Intact Tablet Analyzer
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| Year of introduction |
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| Status |
available |
| Company |
Foss A/S
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| Categories |
Spectrometer ( Molec. ): NIR
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Introduction
Tablet testing has traditionally been conducted by time consuming chemical and physical methods. In less than one minute FOSS Intact Analyzers can provide pharmaceutical manufacturers with information on tablet identity, potency, coating thickness and content uniformity. No crushing, grinding, dissolution or preparation is required. When combined with the Vision Software Package the new InTact Tablet Analyzers allow even non-chemists to obtain accurate test results.
Two systems are available. The standard InTact Analyzer system accepts single tablets and is suited to research and method development. The Intact MultiTab Analyzer includes an integral 30 place AutoSampler for batch or lot sampling, offering faster throughput with less manual effort. Both units are based on the FOSS scanning monochromator and InGaAs detector.
Benefits and Features
- Patented optical design ensures true transmission measurements (U.S. Pat. 5,760,399)
- Analyzes most types of solid dosage forms
- Satisfies USP batch compliance requirements
- Validated Vision ® spectral analysis software
- Analyzers for method development or routine QC testing
- Global assistance and support for streamlined cGMP compliance.
Product Description
InTact Analyzers offer pharmaceutical manufacturers - for the first time - a rapid, reliable test method covering the full array of solid dosage forms: layered, coated or cored tablets, capsules, caplets, gel tabs and gel caps.
The unique, patented InTact optical design operates in transmission mode. This sampling mode provides a representative whole body measurement of the dosage form; rather than only the outside layers as with reflectance measurements.
InTact analysis requires no crushing, grinding, dissolution, or other types of sample preparation. Unlike wet chemical analysis, no solvents or reagents are required with the InTact Analyzers.
InTact Analyzers will streamline solid dosage testing without compromising the results. They are a powerful QC tool for performing a range of tests such as identity, quality, assay, content uniformity, hardness, coating thickness and stability.
FOSS InTact Analyzers are supplied with Vision Spectral Acquisition and Analysis Software for Windows. Vision is fully validated and year-2000 compliant. To help with cGMP regulations, FOSS and its global network of distributors offer extensive support programs.
Model number AP-1600-II
- Monochromator (System II)
- Single position sampling module
- Solid dosage blank
- Custom holder drawing package
- Validated Vision spectral acquisition and analysis software
Model number AP-1610-II
- Monochromator (System II)
- MultiTab Module
- One 30-position carousel
- Custom holder drawing package
- Validated Vision spectral acquisition and analysis software.
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| Specifications |
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Wavelength Range
600-1900nm
Photometric Range
3.0 Au (600-1900nm)
Operating Range
6.0 Au (600-1900nm)
RMS Noise @ 0.0 Absorbance
800-1650nm less than 20 uAU
Data Interval
2.0nm
Scan Speed
1.8 scans/second
Detector
Indium-Gallium-Arsenide (InGaAs)
Wavelength Accuracy Based on instrument to instrument repeatability:
0.15 nm Based on currently accepted wavelength standards.: 0.30nm
Wavelength Precision (SD)
0.01nm
Photometric Linearity
±1.0% of reading
Spectral Bandwidth
9.5nm +/- 1nm
Operating Temperature
15°C to 32°C (60°F to 90°F)Indium-Gallium-Arsenide (InGaAs)
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