Instrument Database:
Shimadzu Europe - AXIMA-QIT MALDI TOF Mass Spectrometer
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Year of introduction |
2002 |
Status |
historical ( out of sale ) |
Company |
Shimadzu Europe
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Categories |
Mass spectrometer: MALDI |
A unique mass analyzer combining the simplicity of MALDI, the power of MSn and accuracy and resolution of TOF for the next generation of structural analysis problems. It can be used to determine protein sequences, proteoglycans, carbohydrates, phosphorylation sites and posttranslational modifications. The AXIMA-QIT™ is designed for the structural characterization of biomolecules, not just mass measurement. It is a unique hybrid instrument employing (schematic): - Matrix assisted laser desorption ionization (MALDI)
- Ion Trap delivering True MSn for structural studies
- Reflectron time of flight (TOF) mass analyzer for accurate mass
The powerful and established LAUNCHPADTM software supports the unique functionality of the AXIMA-QITTM with the addition of INTELLIMARQUETM automated data dependent MS/MS analysis. Key benefits and features:- True MSn for structural studies
- Variable energy CID control
- Quadrupole-ion-trap enabling high resolution precursor selection, control or CID and true MSn
- Time-of-flight analyser enabling high resolution and constant mass accuracy across MS and MSn modes, making database searching and target characterization more effective
- Extremely low acceleration voltage (<100 V) providing excellent tolerance to non-conductive non-flat materials, without compromising sensitivity
- Near-perpendicular laser irradiation for high efficiency ion generation and ion transfer to the quadrupole ion trap
- True MSn capabilities. The unique characteristics of the instrument allow controlled, flexible and complete fragmentation which remains searchable for target identification and characterization.
- High resolution ion selection. Ion selection resolution of >1000 allows discrete analysis of unit Dalton regions of a precursor ion spectrum.
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