native mass spectrometry
Native mass spectrometry (native MS) is defined as the process whereby
large biomolecules and complexes thereof can be transferred from a
three-dimensional, functional existence in a condensed liquid phase to
the gas phase via the process of electrospray ionization mass
spectrometry (ESI-MS). The experimental conditions where this is
possible are so mild that non-covalent interactions, the native state
and the associated biological action and functionality of the
molecule/complex are largely preserved.
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