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Instrument Database:
Bruker Daltonics - microflex LT MALDI-TOF MS
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| Year of introduction |
2005 |
| Status |
historical ( out of sale ) |
| Company |
Bruker Daltonics
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| Categories |
Mass spectrometer: MALDI
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Routine analysis in
- Expression Proteomics
- Clinical Proteomics
- Functional Genomics
The microflex™ LT is an affordable, bench-top MALDI-TOF mass spectrometer for clinical proteomics, as well as for the routine analysis of peptides, proteins and other large molecules.
Due to its gridless ion source, this new instrument provides excellent sensitivity in both positive and negative ion mode. The linear-mode microflex LT is a robust and easy-to-use system for many clinical and life-science laboratories. It operates under the integrated Compass™ software for intuitive operation by non-expert users and in multi-instrument laboratories, with a comprehensive bioinformatics software suite.
The microflex LT benefits from Bruker Daltonics’ patented AnchorChip™ technology which provides exactly-positioned samples on the MALDI-target for robust automatic measurements, as well as a sensitivity boost by up to two orders of magnitude.
The microflex LT system can be an integral module of the CLINPROT™ solution for biomarker discovery and clinical proteomics. CLINPROT is an integrated set of tools for peptide and protein biomarker discovery, identification and validation, including automated magnetic bead based sample preparation methods, and ClinProTools™ comprehensive analysis, visualization and model building software for clinical research.
For pharmaceutical customers, the microflex LT system offers software tools to support customers in achieving 21 CFR Part 11 compliance. Bruker Daltonics also offers optional IQ, OQ and PV services to FDA-regulated customers.
Technical Data
MALDI source
- microScout Ion Source with state-of-the-art pulsed ion extraction (PIE™)
- Target area exactly ¼ of industry standard microtiter plates
- Various 96-spot target types available for specific applications
- Compatible with Bruker Daltonics sample preparation robotics
- Nitrogen laser with variable repetition rate up to 20 Hz
- Patented AnchorChip MALDI target technology for fast automation, increased sequence coverage and 10–100 fold sensitivity increase over stainless steel target holder
TOF Analyzer
- linear only configuration
- positive/negative acceleration voltage
- No maintenance oil-free vacuum technology
- WhisperMode™ erases noise pollution in the lab
- 500 MHz Digitzer board
System solutions
- The microflex LT is fully integrated with Bruker Daltonics’ system solutions
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