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Instrument Database:
Applied Biosystems - 4800 Plus MALDI TOF/TOF™ Analyzer
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| Year of introduction |
2007 |
| Status |
available |
| Company |
Applied Biosystems
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| Categories |
Mass spectrometer: MALDI
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The 4800 Plus MALDI TOF/TOF™ Analyzer is the next generation of tandem time-of-flight MS/MS systems, providing the highest level of protein coverage, throughput, and confidence in quantitative proteomic analysis. The analyzer combines all of the advantages of MALDI in a flexible, easy-to-use, ultra-high-performance mass spectrometer with all the advanced capabilities of ProteinPilot™ v2.0 software. - Ideal system for protein biomarker discovery, providing simultaneous identification and quantitation of up to 8 samples at a time (8-plex workflow) using iTRAQ™ Reagents.
- Fully supports LC MALDI workflows, allowing you to mass analyze without the time constraints of LC.
- Compatible with ProteinPilot v2.0 software for increased protein coverage and confidence in identification and quantitation results.
- OptiBeam™ on-axis laser provides ten times greater sensitivity to identify and quantitate low-abundance proteins in complex biological samples.
- High-resolution precursor ion selection, enabled by the QuanTIS™ precursor selector, lets you detect and identify peptides that other systems miss and makes it easier for you to interpret your data by simplifying MS/MS spectra.
- Simple experiment setup and fast mass analysis maximizes laboratory productivity.
- High-energy, information-rich fragmentation patterns unavailable on other instrument platforms enable you to analyze carbohydrates, lipids, and other biological components.
- Improved on-board computing capabilities handles large scale protein discovery studies with faster processing and automated data backup.
Identify and Quantitate Putative Protein Biomarkers with Confidence
The 4800 Plus MALDI TOF/TOF analyzer offers a new level of sensitivity for identifying and quantifying low abundance putative protein biomarkers. Fully compatible with new iTRAQ™ Reagents – 8plex, the 4800 analyzer provides the most direct path to protein biomarker discovery. An expanded dynamic range enables high confidence identification and quantitation of low-level putative protein biomarkers in complex matrices. Powerful, easy-to-use ProteinPilot v2.0 Software provides simplified quantitation, and automated workflows to get you more quickly from discovery to validation.
The Only MALDI TOF/TOF Analyzer with On-Axis Laser Irradiation
The 4800 Plus Analyzer is the only commercially available MALDI TOF/TOF mass spectrometer with on-axis laser irradiation, enabling sensitivity in the attamole range. Proprietary source modeling algorithms enable low ppm mass detection across the MALDI plate.
Expand Workflows, Increase Throughput
Get the speed, stability, and reliability you need to expand your current experimental workflows and add statistical significance to your experimental results. Quickly and easily increase throughput using automation features that allow you to rapidly and confidently collect the MS/MS spectra that really matter and not waste valuable resources acquiring and evaluating those that don't.
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