EVISA Contact EVISA | Sitemap | Home   
 Advanced search
The establishment of EVISA is funded by the EU through the Fifth Framework Programme (G7RT- CT- 2002- 05112).


Supporters of EVISA includes:

Glossary


cisplatin


Cisplatin is a "first generation" antitumor drug highly effective in the chemotherapy of many forms of cancer. Thge metallodrug is most commonly used to treat testicular, bladder, lung, gullet (oesophagus), stomach and ovarian cancers. The water-soluble platinum complex, after hydrolysis, reacts with the nucleic acid bases of DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
 
IUPAC name: cis-diamminedichloroplatinum(II).


The term "cisplatin" was found in the following pages:



Back








Imprint     Disclaimer

© 2003 - 2024 by European Virtual Institute for Speciation Analysis ( EVISA )