EVISA Print | Glossary on | Contact EVISA | Sitemap | Home   
 Advanced search
The establishment of EVISA is funded by the EU through the Fifth Framework Programme (G7RT- CT- 2002- 05112).

Supporters of EVISA includes:

Scientific publications with participation of EVISA

Research supported by EVISA is meant to:
  • provide easy and robust methods for speciation analysis
  • enhance the quality of analytical results and the information provided by speciation analysis
  • enhance the knowledge about the biological activity, function and toxicity of chemical species
The following studies were done with EVISA participation (newest first):

M. Horstmann, M. Austrup, F. Busch, A. Faust, M. Sperling, U. Karst, D. Clases, Speciation Analysis of Tc radiopharmaceuticals by HPLC-ICP-MS and HPLC-ESI-HRMS, J. Anal. At. Spectrom., 38/10 (2023) 2038-2045. DOI: 10.1039/d3ja00257h

K. Sommer, T. Becker, M. von Bremen-Kühne, M. Gotters, C.D. Quarles, M. Sperling, J. Kudla, U. Karst, Analysis of the elemental species-dependent uptake of lanthanide complexes in Arabidopsis thaliana plants by LA-ICP-MS, Chemosphere, 338 (2023) 139534. DOI: 10.1016/j.chemosphere.2023.139534


Maximilian von Bremen-Kühne, Hassan Ahmadi, Michael Sperling, Ute Krämer, Uwe Karst, Elemental bioimaging of Zn and Cd in leaves of hyperaccumulator Arabidopsis halleri using laser ablation-inductively coupled plasma-mass spectrometry and referencing strategies, Chemosphere 305 (2022) 135267. DOI: 10.1016/j.chemosphere.2022.135267

Karolin Sommer, Michael Sperling, Uwe Karst, Species-dependent interaction of Gd-based contrast agents with humic substances, Chemosphere, 300 (2022) 134528. DOI: 10.1016/j.chemosphere.2022.134528

Olga Reifschneider, Franziska Blaske, Antje Vennemann, Christina Köppen, Michael Sperling, Uwe Karst, Martin Wiemann, Quantitative elemental bioimaging: an antibody-based double-labelling method to quantify the cell-specific distribution of silver nanoparticles in lung tissue sections,  J. Anal. At. Spectrom., 37 (2022) 1084-1089. DOI: 10.1039/D1JA00466B

Rebecca Buchholz, Sebastian Krossa, Maria Karoline Andersen, Michael Holtkamp, Michael Sperling, Uwe Karst, May-Britt Tessem,  A simple preparation protocol for shipping and storage of tissues sections for LA-ICP-MS imaging, Metallomics, 14 (2022) mfac013. DOI: 10.1093/mtomcs/mfac013.


Sabrina K.I. Funke, Michael Sperling, Uwe Karst, Weighted Linear Regression Improves Accuracy of Quantitative Elemental Bioimaging by Means of LA-ICP-MS, Anal. Chem., 93/47 (2021) 15720-27. DOI: 10.1021/acs.analchem.1c03630

Marcel Macke, C. Derrick Quarles Jr, Michael Sperling, Uwe Karst, Fast and Automated Monitoring of Gadolinium-based Contrast Agents in Surface Waters, Water Res., 207 (2021) 117836. DOI: 10.1016/j.watres.2021.117836

Lukas Schlatt, Alexander Köhrer, Cécile Factor, Philippe Robert, Marlène Rasschaert, Michael Sperling, and Uwe Karst, Mild Dissolution/Recomplexation Strategy for Speciation Analysis of Gadolinium from MR Contrast Agents in Bone Tissues by Means of HPLC-ICP-MS, Anal. Chem., 93 (2021) 11398−11405. DOI: 10.1021/acs.analchem.1c01100

C. Erbacher, N. Flothkötter, M. Macke, C.D. Quarles, M. Sperling, J. Müller, U. Karst, A fast and automated separation and quantification method for bromine speciation analyzing bromide and 5-bromo-2'-deoxyuridine in enzymatically digested DNA samples via ion chromatography-inductively coupled plasma-mass spectrometry, J. Chromatogr. A, 1652 (2021) 462370. DOI: 10.1016/j.chroma.2021.462370

I.D. Nordhorn D. Dietrich, C. Verlemann, A. Vennemann, R. Schmid, M. Elinkmann, J. Fuchs, M. Sperling, M. Wiemann, U. Karst, Spatially and size-resolved analysis of gold nanoparticles in rat spleen after intracheal instillation by laser ablation-inductively coupled plasma-mass spectrometry, Metallomics, 13/6 (2021) mfab028. DOI: 10.1093/mtomcs/mfab028

Patrick Bücker, Henning Richter, Alexander Radbruch, Michael Sperling, Marcus Brand, Markus Holling, Veerle Van March, Werner Paulus, Astrid Jeibmann, Uwe Karst, Deposition patterns of iatrogenic lanthanum and gadolinium in the human body depend on delivered chemical binding forms, J. Trace Elem. Med. Biol., 63 (2021) 126665. DOI: 10.1016/j.temb.2020.126665


J.M. Will, C. Erbacher, M. Sperling, U. Karst, A mass spectrometry-based approach gives new insights into organotin-protein interactions, Metallomics, 12 (2020) 1702-1712. DOI: 10.1039/D0MT00171F

S. Richter-Brockmann, K. Garbert, M. von Bremen-Kühne, C.A. Wehe, O. Reifschneider, M. Sperling, L. Wallrad, I. Schmitz-Thom, J. Kudla, U. Karst, Elemental bioimaging of Na distribution in roots of Arabisopsis thaliana using laser ablation -ICP-MS under cold plasma conditions, J. Anal. At. Spectrom., 35/9 (2020) 2057-2063. DOI: 10.1039/D0JA00151A

O. Reifschneider. A. Vennemann, G. Buzanich, M. Radtke, U. Reinholz, H. Riesemeier, J. Hogeback, C. Köppen, M. Großgarten, M. Sperling, M. Wiemann, U. Karst, Revealing Silver Nanoparticles Uptake by Macrophages using SR-µXRF and LA-ICP-MS, Chem. Res. Toxicol., 33/5 (2020) 1250-1255. DOI: 10.1021/acs.chemrestox.9b00507

E. Lützen, M. Holtkamp, I. Stamme, R. Schmid, M. Sperling, M. Pütz, U. Karst, Multimodal imaging of hallucinogens 25C- and 25I-NBOMe on blotter papers, Drug Test. Anal., 12 (2020) 465-471. DOI: 10.1002/dta.2751


O.B. Bauer, O. Hachmöller, O. Borovinskaya, M. Sperling, H.-J. Schurek, G. Ciarimboli, U. Karst, LA_ICP-TOF-MS for rapid, all-elemental and quantitative bioimaging, isotopic analysis and the investigation of plasma processes, J. Anal. At. Spectrom., 34/4 (2019) 694-701. DOI: 10.1039/c8ja00288f

S.A.S. van der Bent, T. Berg, U. Karst, M. Sperling, T. Rustmeyer, Allergic reactions to a green tattoo with nickel as a possible allergen, Contact Dermatitis, 81/1 (2019) 64-66. DOI: 10.1111/cod.13226

Jennifer-Christin Müller, Maximilian Horstmann, Lisa Traeger, Andrea U. Steinbicker, Michael Sperling, Uwe Karst, µXRF and LA-ICP-TQMS for quantitative bioimaging of iron in organ samples of a hemochromatosis model, J. Trace Elem. Med. Biol., 52 (2019) 166-175. DOI: 10.1016/j.jtemb.2018.12.012

Sabrina Kröger, Michael Sperling, Uwe Karst, Quantitative dried blood spot analysis for metallodrugs by laser ablation-inductively coupled plasma-mass spectrometry, J. Trace Elem. Med. Biol., 51 (2019) 50-56. DOI: 10.1016/j.jtemb.2018,09.009

David Clases, Stefanie Fingerhut, Astrid Jeibmann, Michael Sperling, Philip Doble, Uwe Karst, LA-ICP-MS/MS improves limits of detection in elemental bioimaging of gadolinium deposition originating from MRI contrast agents in skin and brain tissues, J. Trace Elem. Med. Biol., 51 (2019) 212-218. doi: 10.1016/j.jtemb.2018.10.021


S. Kröger, A.C. Niehoff, A. Jeibmann, M. Sperling, W. Paulus,  W. Stummer, U. Karst, Complementary Molecular and Elemental Mass Spectrometry Imaging of Human Brain Tumors Resected by Fluorescence-Guided Surgery, Anal. Chem., 90/20 (2018) 12253-60. doi: 10.1021/acs.analchem.8b03516

Joshua Fuchs, Maryam Aghaei, Tilo Schachtel, Michael Sperling, Annemie Bogaerts, Uwe Karst, Impact of the particle diameter on ion cloud formation from gold nanoparticles in ICP-MS, Anal. Chem., 90/17 (2018) 10271-278. doi: 10.1021/scs.analchem.8b02007

Philipp Strohmidel, Michael Sperling, Uwe Karst, Investigations on the binding of ethylmercury from thiomersal to proteins in influenza vaccines, J. Trace Elem. Med. Biol., 50 (2018) 100–104. DOI: 10.1016/j.jtemb.2018.06.011

Anna Hucke, Ga Young Park, Oliver B. Bauer, Georg Beyer, Christina Köppen, Dorothea Zeeh, Christoph A. Wehe, Michael Sperling, Rita Schröter, Marta Kantauskaitè, Yohannes Hagos, Uwe Karst, Stephen J. Lippard and Giuliano Ciarimboli,  Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations, Front. Chem., 6 (2018) #180. DOI: 10.3389/fchem.2018.00180

Stefanie Fingerhut, Michael Sperling, Markus Holling, Thomas Niederstadt, Thomas Allkemper, Alexander Radbruch, Walter Heindel, Werner Paulus, Astrid Jeibmann, Uwe Karst, Gadolinium‑based contrast agents induce gadolinium deposits in cerebral vessel walls, while the neuropil is not affected: an autopsy study, Acta Neuropathol., 136 (2018) 127-138. DOI: 10.1007/s00401-018-1857

Oliver Bolle Bauer, Christina Köppen, Michael Sperling, Hans-Joachim Schurek, Giuliano Ciarimboli, and Uwe Karst, Quantitative Bioimaging of Platinum via Online Isotope Dilution-Laser Ablation-Inductively Coupled Plasma Mass Spectrometry, Anal. Chem., 90 (2018) 7033−7039. DOI: 10.1021/acs.analchem.8b01429

Jennifer-Christin Müller, Josef Lichtmannegger, Hans Zischka, Michael Sperling, Uwe Karst, High spatial resolution LA-ICP-MS demonstrates massive liver copper depletion in Wilson disease rats upon Methanobactin treatment, Journal of Trace Elements in Medicine and Biology 49 (2018) 119–127. DOI: 10.1016/j.jtemb.2018.05.009

David Clases, Michael Sperling, Uwe Karst, Analysis of Metal-based Contrast Agents in Medicine and the Environment, Trends Anal. Chem., 104 (2018) 135-147. DOI: 10.1016/j.trac.2017.12.011

Stefanie Fingerhut, Ann-Christin Niehoff, Michael Sperling, Astrid Jeibmann, Werner Paulus, Thomas Niederstadt, Thomas Allkemper, Walter Heindel, Markus Holling, Uwe Karst, Spatially resolved quantification of gadolinium deposited in the brain of a patient treated with gadolinium-based contrast agents, J. Trace Elem. Med. Biol., 45 (2018) 125-130. DOI: 10.1016/j.jtemb.2017.10.004

Georgina M. Thyssen, Claudia Keil, Melanie Wolff, Michael Sperling, Daniel Kadow, Hajo Haase, Uwe Karst, Bioimaging of the elemental distribution in cocoa beans by means of LA-ICP-TQMS, J. Anal. At. Spectrom., 33 (2018) 187-194. DOI: 10.1039/c7ja00354d


G.M. Thyssen, M. Holtkamp, H. Kaulfürst-Soboll, C.A. Wehe, M. Sperling,  A. von Schaewen, U. Karst, Elemental bioimaging by means of LA-ICP-OES: investigation of the calcium, sodium and potassium distribution in tobacco plant stems and leaf petioles,  Metallomics, 9/6 (2017) 676-684. doi:  10.1039/C7MT00003K

Oliver Hachmöller, Michaela Aichler, Kristina Schwamborn, Lisa Lutz, Martin Werner , Michael Sperling, Axel Walch and Uwe Karst, Investigating the influnce of standard staining procedures on the copper distribution and concentration  in Wilson's disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry, J. Trace Elem. Med.  Biol., 44 (2017) 71–75. DOI: 10.1016/j.jtemb.2017.06.002

Oliver Hachmöller, Andree Zibert, Hans Zischka, Michael Sperling, Sara Reinartz Groba, Inga Grünewald, Eva Wardelmann, Hartmut H.-J. Schmidt, Uwe Karst, Spatial investigation of the elemental distribution in Wilson’s disease liver after D-penicillamine treatment by LA-ICP-MS, J. Trace Elem. Med. Biol., 44 (2017) 26-31. DOI: 10.1016/j.jtemb.2017.05.008
David Clases, Marvin Birka, Michael Sperling, Andreas Faust, Uwe Karst, Isobaric dilution analysis as a calibration tool for long lived radionuclides in ICP-MS, J. Trace Elem. Med. Biol., 40 (2017) 97–103. DOI: 10.1016/j.jtemb.2017.01.002


Marvin Birka, Jörg Roscher, Michael Holtkamp, Michael Sperling, Uwe Karst, Investigating the stability of gadolinium based contrast agents towards UV radiation, Water Res., 91 (2016) 244-250. DOI: 10.1016/j.watres.2016.01.012

Oliver Hachmöller, Ana Guilherme Buzanich, Michaela Aichler, Martin Radtke, Dörthe Dietrich, Kristina Schwamborn, Lisa Lutz, Martin Werner, Michael Sperling, Axel Walch and Uwe Karst, Elemental bioimaging and speciation analysis for the investigation of Wilson’s disease using µXRF and XANES, Metallomics, 8 (2016) 648-653. DOI: 10.1039/c6mt00001k

Marvin Birka, Christoph A. Wehe, Oliver Hachmöller, Michael Sperling, Uwe Karst, Tracing gadolinium-based contrast agents from surface water to drinking water by means of speciation analysis, J. Chromatogr. A, 1440 (2016) 105-111. DOI: 10.1016/j.chroma.2016.02.050

Oliver Hachmöller, Michaela Aichler, Kristina Schwamborn, Lisa Lutz, Martin Werner, Michael Sperling, Axel Walch, Uwe Karst, Element bioimaging of liver needle biopsy specimens from patients with Wilson’s disease by laser ablation-inductively coupled plasma-mass spectrometry, J. Trace Elem. Med.  Biol., 35 (2016) 97–102. DOI: 10.1016/j.jtemb.2016.02.001

Jens Hogeback, Miriam Schwarzer, Christoph A. Wehe, Michael Sperling and Uwe Karst, Investigating the adduct formation of organic mercury species with carbonic anhydrase and hemoglobin from human red blood cell hemolysate by means of LC/ESI-TOF-MS and LC/ICP-MS, Metallomics, 8 (2016) 101-107. DOI: 10.1039/c5mt00186b


Chun Kong Mak, Christoph A. Wehe, Michael Sperling, Uwe Karst, Identification and quantification of electrochemically generated metabolites of thyroxine by means of liquid chromatography/electrospray-mass spectrometry and countergradient liquid chromatography/inductively coupled plasma-mass spectrometry, J. Chromatogr. A, 1419 (2015) 81–88. DOI: 10.1016/j.chroma.2015.09.076

C. Köppen, O. Reifschneider, I. Castanheira, M. Sperling, U. Karst and G. Ciarimboli, Quantitative imaging of platinum based on laser ablation-inductively coupled plasma-mass spectrometry to investigate toxic side effects of cisplatin, Metallomics, 7 (2015) 1595-1603. DOI: 10.1039/c5mt00226e

Rebecca Niehaus, Michael Sperling and Uwe Karst, Study on aerosol characteristics and fractionation effects of organic standard materials for bioimaging by means of LA-ICP-MS, J. Anal. At. Spectrom., 30 (2015) 2056-2065. DOI: 10.1039/c5ja00221d

Christoph A. Wehe, Georgina M. Thyssen, Christina Herdering, Indra Raj, Giuliano Ciarimboli, Michael Sperling, Uwe Karst, Elemental Bioimaging by Means of Fast Scanning Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry, J. Am. Soc. Mass Spectrom. 26/8 (2015) 1274-1282. DOI: 10.1007/s13361-015-1141-y

Olga Reifschneider,  Kristina S. Wentker, Klaus Strobel, Rebecca Schmidt, Max Masthoff, Michael Sperling, Cornelius Faber, Uwe Karst, Elemental Bioimaging of Thulium in Mouse Tissues by Laser Ablation-ICPMS as a Complementary Method to Heteronuclear Proton Magnetic Resonance Imaging for Cell Tracking Experiments, Anal. Chem. , 87 (2015)  4225-4230. DOI: 10.1021/ac504363q

Olga Reifschneider, Christian L. Schütz, Christoph Brochhausen, Gabriele Hampel, Tobias Ross, Michael Sperling, Uwe Karst, Quantitative bioimaging of p-boronophenylalanine in thin liver tissue sections as a tool for treatment planning in boron neutron capture therapy, Anal. Bioanal. Chem.  407 (2015) 2365–2371. DOI 10.1007/s00216-014-8012-4

Marvin Birka, Kristina S. Wentker, Elke Lusmöller, Brigit Arheilger, Christoph A. Wehe, Michael Sperling, Rudolf Stadler, Uwe Karst, Diagnosis of Nephrogenic Systemic Fibrosis by means of Elemental Bioimaging and Speciation Analysis, Anal. Chem. 87 (2015) 3321-3328. DOI: 10.1021/ac504488k


Christoph A. Wehe, Imke Pieper, Michael Holtkamp, Georgina M. Thyssen, Michael Sperling, Tanja Schwerdtle, Uwe Karst, On-line species-unspecific isotope dilution analysis in the picomolar range reveals the time- and species-depending mercury uptake in human astrocytes, Anal Bioanal Chem, 406 (2014) 909–1916. DOI 10.1007/s00216-013-7608-4

Christoph A. Wehe, Georg Beyer, Michael Sperling, Giuliano Ciarimboli, Uwe Karst, Assessing the intracellular concentration of platinum in medulloblastoma cell lines after Cisplatin incubation, J. Trace Elem. Med. Biol., 28 (2014) 166–172. doi: 10.1016/j.jtemb.2014.01.001

Stefan Trümpler, Björn Meermann, Sascha Nowak, Wolfgang Buscher, Uwe Karst, Michael Sperling, In vitro study of thimerosal reactions in human whole blood and plasma surrogate samples, J. Trace Elem. Med. Biol., 28 (2014) 125–130. doi: 10.1016/j.jtemb.2014.01.006

Christoph A. Wehe, Ann-Christin Niehoff, Georgina M. Thyssen, Michael Sperling, Uwe Karst, Rapid cell mode switching and dual laser ablation inductively coupled plasma mass spectrometry for elemental bioimaging, Rapid Commun. Mass Spectrom., 28 (2014) 2627–2635. DOI: 10.1002/rcm.7054

Franziska Blaske, Olga Reifschneider, Georg Gosheger, Christoph A. Wehe, Michael Sperling, Uwe Karst, Gregor Hauschild, Steffen Höll, Elemental Bioimaging of Nanosilver-Coated Prostheses Using X-ray Fluorescence Spectroscopy and Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry, Anal. Chem., 86 (2014) 615-620.  doi: 10.1021/ac4028577

Sascha Nowak, Monika Gesell, Michael Holtkamp, Andy Scheffer, Michael Sperling, Uwe Karst, Wolfgang Buscher, Low gas flow inductively coupled plasma optical emission spectrometry for the analysis of food samples after microwave digestion,  Talanta, 129 (2014) 575–578. doi: 10.1016/j.talanta.2014.06.045

Ann-Christin Bülter, Aline Moosmann, Judith Söbbing, Arno Wiehe,  Dennis Mulac, Christoph Alexander Wehe, Olga Reifschneider, Franziska Blaske, Sylvia Wagner, Michael Sperling, Hagen von Briesen, Klaus Langer, Uwe Karst, A Palladium Label to Monitor Nanoparticle-Assisted Drug Delivery of a Photosensitizer into Tumor Spheroids by Elemental Bioimaging,  Metallomics, 6/1 (2014) 77-81. DOI: 10.1039/C3MT00223C


Christina Herdering, Olga Reifschneider, Christoph A. Wehe, Michael Sperling, Uwe Karst, Ambient molecular imaging by laser ablation atmospheric pressure chemical ionization mass spectrometry, Rapid Commun. Mass Spectrom., 27 (2013) 2595–2600. DOI: 10.1002/rcm.6727

Christina Herdering, Christoph A. Wehe, Olga Reifschneider, Indra Raj, Giuliano Ciarimboli, Kurt Diebold, Christoph Becker, Michael Sperling, Uwe Karst, Laser ablation based bioimaging with simultaneous elemental and molecular mass spectrometry: towards spatially resolved speciation analysis, Rapid Commun. Mass Spectrom., 27 (2013) 2588–2594. DOI: 10.1002/rcm.6726

Franziska Blaske, Lisa Stork, Michael Sperling, Uwe Karst, Adduct formation of ionic and nanoparticular silver with amino acids and glutathione, J. Nanopart. Res., 15 (2013) 1928. DOI 10.1007/s11051-013-1928-3

Olga Reifschneider, Christoph A. Wehe, Indra Raj, Jens Ehmcke, Giuliano Ciarimboli, Michael Sperling, Uwe Karst, Quantitative bioimaging of platinum in polymer embedded mouse organs using laser ablation ICP-MS, Metallomics, 5 (2013) 1440-1447. DOI: 10.1039/c3mt00147d

Marvin Birka, Christoph A. Wehe, Lena Telgmann, Michael Sperling, Uwe Karst, Sensitive quantification of gadolinium-based magnetic resonance imaging contrast agents in surface waters using hydrophilic interaction liquid chromatography and inductively coupled plasma sector field mass spectrometry, J. Chromatogr. A, 1308 (2013) 125-131. DOI:    10.1016/j.chroma.2013.08.017

Michael Holtkamp, Tim Elseberg, Christoph A. Wehe, Michael Sperling, Uwe Karst, Complexation and oxidation strategies for improved TXRF determination of mercury in vaccines, J. Anal. At. Spectrom., 28 (2013) 719-723. DOI: 10.1039/c3ja00002h

Olga Reifschneider, Christoph A. Wehe, Kurt Diebold, Christoph Becker, Michael Sperling, Uwe Karst, Elemental bioimaging of haematoxylin and eosin-stained tissues by laser ablation ICP-MS, J. Anal. At. Spectrom., 28 (2013) 989-993. DOI: 10.1039/c3ja50046b

Christine Brauckmann, Christoph A. Wehe, Michael Kieshauer, Claudia Lanvers-Kaminsky,  Michael Sperling, Uwe Karst, The interaction of platinum-based drugs with native biologically relevant proteins, Anal. Bioanal. Chem., 405 (2013) 1855-1864. DOI: 10.1007/s00216-012-6410-z

Christine Brauckmann, Helene Faber, Claudia Lanvers-Kaminsky, Michael Sperling, Uwe Karst, Influence of cimetidine and its metabolites on Cisplatin—Investigation of adduct formation by means of electrochemistry/liquid chromatography/electrospray mass spectrometry, J. Chromatogr. A., 1279 (2013) 49–57. DOI: 10.1016/j.chroma.2012.12.069

Lena Telgmann, Michael Sperling, Uwe Karst, Speciation of Gd-based MRI contrast agents in biological and environmental samples: A review, Anal. Chim. Acta, 764 (2013) 1-16. DOI: 10.1016/j.aca.2012.12.007

Michael Sperling, Uwe Karst, Metallomics: an emerging interdisciplinary science, Anal. Bioanal. Chem., 405/6 (2013) 1789-1790. DOI: 10.1007/s00216-012-6619-x  


L. Telgmann, C.A. Wehe, M. Birka, J. Künnemeyer, S. Nowak, M. Sperling, U. Karst, Speciation and Isotope Dilution Analysis of Gadolinium-Based Contrast Agents in Wastewater, Environ. Sci. Technol., 46 (2012) 11929-11936. DOI: 10.1021/ES301981Z

L. Telgmann, C.A. Wehe, J. Künnemeyer, A.-C. Bülter, M. Sperling, U. Karst, Speciation of Gd-based MRI contrast agents and potential products of transmetalation with iron ions or parenteral iron supplements, Anal. Bioanal. Chem., 404 (2012) 2133-2141. DOI: 10.1007/S00216-012-6404-X

M. Holtkamp, C.A. Wehe, F. Blaske, C. Holtschulte, M. Sperling, U. Karst, Nitrogen purged TXRF for the quantification of silver and palladium, J. Anal. Atomic Spectrom., 27 (2012) 1799-1802. DOI: 10.1039/C2JA30117B

Bjoern Meermann, Michael Sperling, Hyphenated techniques as tools for speciation analysis of metal-based pharmaceuticals: developments and applications, Anal. Bioanal. Chem., 403 (2012) 1501–1522. DOI: 10.1007/S00216-012-5915-9

Lena Telgmann, H. Faber, S. Jahn, D. Melles, H. Simon, M. Sperling, U. Karst, Identification and Quantification of Potential Metabolites of Gd-Based Contrast Agents by Electrochemistry/Separations/Mass Spectrometry, J. Chromatogr. A, 1240 (2012) 147–155.DOI: 10.1016/J.CHROMA.2012.03.088


Michael Sperling, Joanna Szpunar, Speciation Issue: Editorial, J. Anal. At. Spectrom., 26 (2011) 22. DOI: 10.1039/c0ja90031a

C.A. Wehe, J. Bornhorst, M. Holtkamp, M. Sperling, H.-J. Galla, Tanja Schwerdtle, U. Karst, Fast and low sample consuming quantification of manganese in cell nutrient solutions by flow injection ICP-QMS, Metallomics, 3/12 (2011) 1291–1296. DOI: 10.1039/C1MT00170A

L. Telgmann, M. Holtkamp, J. Künnemeyer, C. Gelhard, M. Hartmann, A. Klose, M. Sperling, U. Karst, Simple and rapid quantification of gadolinium in urine and blood plasma samples by means of total reflection X-ray fluorescence (TXRF), Metallomics, 30 (2011) 1766-1773. DOI: 10.1039/c1mt00054c

R. Janzen, M. Schwarzer, M. Sperling, M. Vogel, T. Schwerdtle, U. Karst, Adduct formation of Thimerosal with human and rat hemoglobin: a study using liquid chromatography coupled to electrospray time-of-flight mass spectrometry (LC/ESI-TOF-MS), Metallomics, 3/8 (2011) 847–852. DOI: 10.1039/C1MT00043H


S. Bomke, M. Sperling, U. Karst, Organometallic derivatizing agents in bioanalysis, Anal. Bioanal. Chem., 397 (2010) 3483-3494. DOI: 10.1007/s00216-010-3611-1

A. Wilken, R. Janzen, M. Holtkamp, S. Nowak, M. Sperling, M. Vogel, U. Karst, Investigation of the interaction of Mercurochrome constituents with proteins using liquid chromatography/mass spectrometry, Anal. Bioanal. Chem., 397 (2010) 3525-3532. DOI: 10.1007/S00216-010-3842-1


S. Trümpler, S. Nowak, B. Meermann, G. A. Wiesmüller, W. Buscher, M. Sperling, U. Karst, Detoxification of mercury species—an in vitro study with antidotes in human whole blood , Anal. Bioanal. Chem., 395 (2009) 1929-1935. DOI: 10.1007/s00216-009-3105-1

S. Trümpler, W. Lohmann, B. Meermann, W. Buscher, M. Sperling, U. Karst, Interaction of Thimerosal with Proteins - Ethylmercury Adduct Formation of Human Serum Albumin and b-Lactoglobulin A, Metallomics, 1 (2009) 87-91. DOI: 10.1039/b815978e

before 2008

Kevin Francesconi, Michael Sperling, Speciation analysis with HPLC-mass spectrometry: time to take stock, The Analyst, 130 (2005) 998-1001. DOI: 10.1039/b504485p

M. Sperling, W. Buscher, O.F.X. Donard, R. Cornelis, L. Ebdon, Transfer of Know-how and Knowledge in the Area of Speciation Analysis from research Institutions to Industry - The European Virtual Institute for Speciation Analysis (EVISA), RMZ-Materials and Geoenvironment, 51 (2004) 2030-2032.

R. Cornelis, W. Buscher, M. Sperling, O.F.X. Donard, N. Proust, E. Rosenberg, R. Milacic, The EC networking on elemental speciation revisited, Accred. Qual. Assur., 9 (2004) 268-271 (2004). DOI: 10.1007/s00769-004-0761-x

last time modified: October 22, 2023


Imprint     Disclaimer

© 2003 - 2024 by European Virtual Institute for Speciation Analysis ( EVISA )